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00:00:00 – 00:09:41
Dr. Tsuji's groundbreaking research on hair stem cell multiplication offers hope for a potential cure for hair loss by generating new follicles from a single scalp hair follicle. Despite financial setbacks, Dr. Tsuji revamped Organ Technology into Organ Tech and partnered with Kobayashi Pharmaceutical for hair regeneration trials. The expedited approval process in Japan facilitates regenerative treatments. Clinical trials aim to confirm safety and efficacy, although challenges like DHT resistance and preventative treatments may arise. The technology targets effective hair follicle regeneration to cover balding areas. The development could revolutionize hair loss treatment, showcasing promise for the future of regenerative medicine.
00:00:00
In this segment of the video, the narrator provides a major update on Dr. Tsuji’s research in hair stem cell multiplication. Dr. Tsuji has been focusing on creating fully polarized hair follicle germs using two types of stem cells that develop hair follicles during the prenatal period. These stem cells are obtained from the donor area, multiplied in culture, and placed in a 3D environment to mimic the skin for follicular primordium formation. It is suggested that this method could potentially offer a cure for hair loss, as a single hair follicle from the scalp could generate a hundred new hair follicles.
00:03:00
In this segment of the video, it is discussed how the venture company, Organ Technology, faced financial constraints leading to a halt in operations. Dr. Tsuji and Reichen sought public donations of nearly five million dollars to initiate human clinical trials for hair follicle regenerative medicine. By 2023, Dr. Tsuji took over Organ Technology’s debt, renamed the company to Organ Tech, and secured funding for hair regeneration trials in 2024 with Kobayashi Pharmaceutical. They showcased their technology at a startup program and Dr. Tsuji plans to start free medical care using their regenerative seeds by fiscal year 2026. Japan offers a favorable and fast approval pathway for stem cell therapies, easing the path for regenerative treatments.
00:06:00
In this segment of the video, it is discussed that companies conducting phase 3 clinical trials for hair regenerative technology may only need to demonstrate efficacy with as few as 10 patients in some cases. The financial security of Dr. Tsuji’s team allows them to move forward with clinical trials to confirm safety and efficacy. It is noted that while clinical trials were delayed, the technology shows promise as one of the closest options for hair multiplication. However, a potential disadvantage is that extracted cells may not be 100% DHT resistant, necessitating preventative treatments like anti-androgens. The technology aims to regenerate hair follicles effectively to cover balding scalps. Future human clinical trials will hopefully address challenges and lead to successful outcomes.
00:09:00
In this segment of the video, the speaker discusses how a new development could be a game changer for the hair loss community. They mention keeping viewers updated on any further information. They caution that updates from the mentioned individuals may be slow due to their history. The speaker asks for viewers’ thoughts on Dr. Tsuji and his hair regeneration technology. Finally, they thank the audience and encourage them to like the video, ending with a promise for more content in the future.